Benefit of genetic testing over using medical history to identify the possibility of future diseases
Genes are the instructions that tell our bodies how to work properly. If there is a change in any of our genes (mutations), it may affect what that gene is supposed to do and may cause different health or medical problems.
You can think of a gene as a sentence in a book. If there is a change in any of the letters or if any of the words are missing (mutations), it will affect what that sentence was supposed to say.
– Mutations are caused by changes or misspellings in our genes and mutational effects can be beneficial, harmful, or neutral, depending on their context or location. Gene mutations can be recessive or dominant and dominant genes can be active or stay inactive.
– Genes can become active at any time due to foods you eat, the environment etc. Genetic testing allows you to know your genetic predispositions to diseases so you can make changes to prevent diseases and lead a healthier lifestyle.
Knowledge is power and prevention is better than cure.
In the case of most diseases, the earlier you catch them, the better chance you have at treating them successfully.
Mutation can be recessive or dominant
Certain diseases are recessive. If you carry just one recessive gene mutation, you’ll never develop a disease from that mutation. But you can pass it on to your children. If your partner has the same mutation, the mutation will become dominant in your children.
This means that a person may develop a disease only if they inherited a recessive gene from both parents or inherited dominant genes. Carrying just one of the defective genes(recessive) causes no symptoms. Carrying two of the same defective genes(dominant) raises your risk of having health and medical problems.
Human diseases are multigenic, meaning they result from mutations in multiple genes. Mutational effects can be beneficial, harmful, or neutral, depending on their context or location. Some gene mutations affect only the individual that carries them, while others affect all of the carrier organism’s offspring, and further descendants.
Many genetic changes are unique to a family. However, even in families and individuals who have the exact same mutation, there can be variability in how the condition affects each family member. And, It is also possible for a person to be the first in their family to be affected by a certain gene mutation. In addition, mutations might not cause health issues and can skip family members or generations.
Example: Cancer genes BRCA1/2
– For women with a personal or family history of breast, ovarian, tubal, or peritoneal cancer or an ancestry associated with cancer, The US Preventative Services Task Force (USPSTF) recommends that they get a genetic test for 1 and 2 (BRCA1/2) gene mutations for risk assessment.
– USPSTF is against routine risk assessment for women whose personal or family history or ancestry is not associated with potentially harmful BRCA1/2 gene mutations.
**in this case, a medical history is useless because diseases can occur sporadically and not affect all family members. Doctors only perform medical genetic testing if you have symptoms or a family history of a disease. Genetic mutations can skip family members and generations. A deceased family member could have carried a gene mutation and never developed the disease. A living relative could also be carrying a gene mutation and never develop a disease.
Without a genetic testing and analysis, it is impossible to know if a person is a carrier.
Waiting to have symptoms before getting a medical genetic test can end up being costly, emotionally draining and in some cases, it might be too late.
Take control of your health and get BioActify preventative genetic test. Knowledge is power and prevention is better than cure.